SPM Active

SPM Active SO

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Specialized Pro-resolving Mediators
SPM Active is a revolutionary nutritional product developed through advanced fractionation technology featuring standardized levels of SPMs (specialized pro-resolving mediators) found in fish oil. Designed to support the body’s natural capacity to respond to physical challenges and resolve physical stress.*


  • A breakthrough in tissue health and immune response support*
  • Supports healthy immune cell (i.e., macrophage) resolution-related activities*

Label & Supplement Facts

Ingredient Amount Daily Value
Calories from Fat  
Total Fat 0.5 g  <1%* 
Cholesterol <2%* 
Active Portion of Fractionated Marine Lipid Concentrate† 500 mg  ** 
SPM content standardized to    
18-hydroxy-eicosapentaenoic acid (18-HEPE) and    
17-hydroxy-docosahexaenoic acid (17-HDHA)    
Ingredients: Fractionated marine lipid concentrate [(anchovy and sardine oil, and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, water, pectin, and sorbitol), and lemon oil. 

Contains: Fish (anchovy and sardine).

Directions: Take two softgels once daily or as directed by your healthcare practitioner.

This product is non-GMO and gluten free.

 If pregnant, nursing, or taking nutritional supplements or medications, consult your healthcare practitioner before use. Keep out of the reach of children.

Storage: Keep tightly closed in a cool, dry place.

Do not use if safety seal is missing or broken.


*Percent Daily Values are based on a 2,000 calorie diet.
**Daily Value not established.